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Enzyme Research 是一家擁有超過25年的酶研究的實驗室，生產(chǎn)和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年Enzyme Research Laboratories為科學家參與止血和血栓形成的研究提供了寶貴支持。Enzyme Research通過不斷追求產(chǎn)品的zui高品質(zhì)，贏得了世界各地凝血研究實驗室的信任。

Human Kallikrein

HPKa 1303             Human Kallikrein

Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain （Mr 52kD） and light chains （Mr either 36 or 33 kD） linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient （1%） = 11.7
Molecular Weight = ~86,000 daltons

 

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